Magnetic Resonance Functional Imaging

Outline

Mind Map

Learning Objectives

Teaching Visuals

Online Module
(Requires Enrollment)

Text Reference

 

Outline and Learning Guide


INTRODUCTION AND OVERVIEW

DIFFUSION IMAGING

Brownian Motion and Diffusion

Diffusion Coefficient

Apparent Diffusion Coefficient (ADC)

Diffusion Direction

The Imaging Process

Diffusion Sensitivity

Diffusion-Weighted Images

ADC Map Images

BLOOD OXYGENATION LEVEL DEPENDENT (BOLD) CONTRAST

PERFUSION IMAGING

MIND MAP and  SUMMARY

 

 

Learning Objectives

 
  • Describe and compare the general characteristics of a functional MR image to those of a more conventional T1 or T2 weighted image.
  • Describe and illustrate Brownian motion.
  • Describe and illustrate the process of diffusion as it applies to fluid molecules within the human body.
  • Identify and briefly describe the principle factor that determines the diffusion rate in a medium like human tissue.
  • Explain the concept of diffusion coefficient.
  • Explain the concept of the apparent diffusion coefficient (ADC) and how it applies to MR imaging.
  • Identify and briefly describe the conditions that cause diffusion to have a directional characteristic in a medium like human tissue.
  • Describe the general characteristics of a diffusion weighted image and the tissue conditions that affect signal intensity and image brightness.
  • Describe and illustrate the imaging process that can be used to produce images with contrast based on the diffusion characteristics of tissue.
  • Identify and briefly describe the factors within the imaging process that can be changed to produce different values for the diffusion sensitivity protocol parameter.
  • Explain and illustrate the significance of the diffusion sensitivity protocol factor value with respect to the image contrast relationship on diffusion.
  • Describe the general characteristics of an apparent diffusion coefficient (ADC) map image and compare it to a diffusion weighted image.
  • Describe and illustrate the general characteristics of a diffusion tensor image and the tissue characteristics that affects it's appearance.
  • Describe the general concept of a apparent diffusion coefficient (ADC) map image trace.
  • Compare the magnetic characteristics of oxyhemoglobin and deoxyhemoglobin and briefly explain the significance in MR imaging.
  • Describe the concept and process of blood oxygenation level dependent (BOLD) contrast imaging.
  • Describe the concept and process of perfusion imaging with MR.
  • Explain why a rapid imaging acquisition method is required for perfusion imaging.
  • Explain why and how signal intensity is related to tissue perfusion in the process of perfusion imaging.
  • Briefly describe the principle of obtaining blood perfusion parameter values (regional volume, flow, etc) with the perfusion imaging method.
     

 

Text Reference

Chapter 13

Magnetic Resonance Imaging: Principles, Methods, and Techniques
Medical Physics Publishing,  http://www.medicalphysics.org

 

 

Mind Map